Diseases that require renal replacement therapy, such as kidney failure, uremia, etc
Conditions
Interventions
Conventional anticoagulant group:Conventional Sodium Citrate Anticoagulation Method
Ordinary segmented anticoagulant group:Fixed ratio segmented sodium citrate anticoagulant
Improved segmented anticoagulant group:Segmented sodium citrate anticoagulant with multi-point dynamic adjustment
Sponsors
Zhejiang Provincial Hospital of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged >= 18 years old; 2. Patients treated with CVVH post dilution (or pre+post dilution) using calcium replacement solution; 3. Patients treated with sodium citrate anticoagulation; 4. CVVH treatment time >= 24 hours; 5. Informed consent and signing of informed consent form;
Exclusion criteria
Exclusion criteria: 1. Patients allergic to sodium citrate and other related materials; 2. Patients with contraindications to sodium citrate anticoagulation, such as severe liver dysfunction (total bilirubin>60 µ mol/L), hypoxemia (arterial oxygen partial pressure<60mmHg), etc; 3. Pregnant and lactating patients;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Venous coagulation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Direct medical costs;Filter coagulation rate;Service life of extracorporeal circulation pathway;Systemic bleeding situation; | — |
Countries
China
Contacts
Public ContactYinlong Li
Zhejiang Provincial Hospital of TCM
Outcome results
None listed