healthy human
Conditions
Interventions
treatment 1:20Hz tTIS
control:sham tTIS
treatment2:80Hz tTIS
Sponsors
The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Aged between 18 and 45 years, with no history of clearly diagnosed neurological, cardiovascular, or psychiatric diseases; (2) Being in a stable physical condition during the trial and at least one month prior to its initiation, without having taken any drugs that may significantly affect central nervous system excitability or cerebral blood flow; (3) Upper limb function: having normal function of both upper limbs, being right-handed, scoring Grade 5 in manual muscle testing, and free from sensory disturbances; (4) Consciousness and communication: being conscious, capable of normal communication, and without cognitive impairment; (5) Voluntarily participating in this trial and signing a written informed consent form.
Exclusion criteria
Exclusion criteria: (1) Subjects with intracranial implanted metal objects, pacemakers, or cochlear implants; (2) Subjects with deep sedation induced by general anesthetics (e.g., propofol) or centrally acting sedatives (e.g., benzodiazepines, opioids); (3) Subjects with frequent cardiac arrhythmias or frequent epileptic seizures; (4) Subjects with a history of mental illness, substance abuse, or alcoholism; (5) Subjects who have participated in other clinical trials involving brain stimulation or neuromodulation within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nine Hole Peg Test, 9HPT; | — |
Secondary
| Measure | Time frame |
|---|---|
| Grip Strength Test;choice reaction time task, CRTT;fMRI;EEG;fNIRS;tms; | — |
Countries
china
Contacts
Public ContactMin Su
The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
Outcome results
None listed