Targeted Screening of Gut Microbiota Metabolites as Clinical Biomarkers and Their Regulatory Mechanisms in CKD

Clinical Research Protocol for Targeted Screening of Gut Microbiota Metabolites as Clinical Biomarkers and Their Regulatory Mechanisms in CKD

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2600117434

Enrollment

Unknown

Registered

2026-01-23

Start date

2026-02-28

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease

Interventions

Chronic Kidney Disease:None

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Study Population? Patients diagnosed with Chronic Kidney Disease (CKD) according to the KDIGO (Kidney Disease: Improving Global Outcomes) guidelines. 2. Inclusion Criteria (1) No use of antimicrobial agents, or any medications or technical interventions that may affect the diversity and/or activity of the gut microbiota, within the recent 1 month. (2) Voluntarily sign the informed consent form (if exempt, this item shall be deleted). (3) Age requirement: = 18 years and = 55 years.

Exclusion criteria

Exclusion criteria: 1. Use of antimicrobial agents, or any medications or technical interventions that may affect the diversity and/or activity of the gut microbiota, within the recent 1 month; 2. Age >55 years or <18 years.

Design outcomes

Primary

Measure	Time frame
Demographic data (Date of birth, Sex, Abbreviated name);Medical History and Physical Examination (Height, Weight, Disease Severity Assessment; Past and Present History of CKD, and Family History);Urinalysis (urine protein, urine red blood cells, urine glucose, white blood cells, urine specific gravity);Complete Blood Count(Whole Blood Metabolomics Analysis);Routine Stool Test (Gut Microbiota Diversity Analysis);	—

Measure

Time frame

Demographic data (Date of birth, Sex, Abbreviated name);Medical History and Physical Examination (Height, Weight, Disease Severity Assessment; Past and Present History of CKD, and Family History);Urinalysis (urine protein, urine red blood cells, urine glucose, white blood cells, urine specific gravity);Complete Blood Count(Whole Blood Metabolomics Analysis);Routine Stool Test (Gut Microbiota Diversity Analysis);

—

Countries

China

Contacts

Public ContactXun Tianrong

Shenzhen Hospital of Southern Medical University

xtr21200791@smu.edu.cn+86 156 2506 5210

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026