Acute Aortic Syndromes
Conditions
Interventions
Gold Standard:CTA (Computed Tomography Angiography), TEE (Transesophageal Echocardiography), and MRA (Magnetic Resonance Angiography)
Index test:AI-assisted non-contrast CT combined with ADDRS
Sponsors
The First Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Presented to the emergency department with non-traumatic acute chest pain (defined as pain, pressure, tightness, or discomfort involving the chest, shoulder, arm, neck, back, upper abdomen, or jaw, as well as associated symptoms such as shortness of breath and fatigue). 2.The attending physician considered acute aortic syndrome (AAS) as one of the differential diagnoses. 3.Age >18 years, with no restriction on sex.
Exclusion criteria
Exclusion criteria: 1. After an initial medical assessment, the attending physician has an objectively established alternative diagnosis; 2. Clinical severity or other conditions that do not allow for a complete assessment/appropriate enrollment; 3. Pregnancy; 4. Age under 18; 5. Inability to follow up; 6. Inability to obtain informed consent; 7. Refuse to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| failure rate of negative AI-assisted non-contrast CT results for ruling out AAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive Predictive Value, PPV;Positive Predictive Value, PPV;Sensitivity;Specificity;Efficiency of AI-assisted non-contrast CT negative results in ruling out AAS in suspected AAS patients; | — |
Countries
China
Contacts
Public ContactHongkun Zhang
The First Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed