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A study on the association between serum sTREM2, VA, RA levels and cognition and symptoms of autism in Children

A study on the association between serum sTREM2, VA, RA levels and cognition and symptoms of autism in Children

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117414
Enrollment
Unknown
Registered
2026-01-23
Start date
2024-12-20
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism Spectrum Disorder

Interventions

Sponsors

Children's Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.The Department of Child Health Care (Health Management Department) at the Children's Hospital Affiliated to Chongqing Medical University is recruiting 105 healthy children and 105 children with ASD. Diagnoses will be conducted by professional physicians, with ASD diagnoses required to meet DSM-5 diagnostic criteria.

Exclusion criteria

Exclusion criteria: 1.The patient or family members are unable to cooperate with blood collection and testing; 2.History of other neurological diseases, chromosomal diseases, hereditary metabolic diseases and other major medical diseases, such as audiovisual impairment, epilepsy, phenylketonuria, nodular encephalosclerosis, neurofibromas, severe traumatic brain injury, autoimmune diseases, endocrine, cardiovascular, pulmonary, liver and kidney diseases. The patient's legal guardian refuses to participate in the program. 3.The patient's legal guardian refused to participate in the project;

Design outcomes

Primary

MeasureTime frame
Serum VA concentration in children with autism;cognitive level and symptom severity in children with autism;Serum RA concentration in children with autism;Serum sTREM2 concentration in children with autism;

Countries

China

Contacts

Public ContactHua Wei

Children's Hospital of Chongqing Medical University

weihua6280@163.com+86 23 6837 0551

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026