Respiratory grunting
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. It meets the diagnostic criteria of the 5th edition of "Practical Neonatology" edited by Shao Xiaomei et al.: There is a phenomenon of respiratory grunting, and one of the following conditions exists: (tachycardia > 160 beats per minute; depression of the intercostal spaces or supraclavicular fossa; nasal flaring; respiratory grunting; hypoxemia; gestational age > 34 weeks (late preterm infants + full-term infants)); 2. Within 6 hours after birth, there are manifestations of respiratory distress such as rapid breathing, grunting, nasal flaring or cyanosis, and respiratory support or oxygen therapy is required; 3. The lung ultrasound diagnosis is consistent with neonatal hyaline lung disease (TTN); 4. After admission, bedside lung ultrasound examination and follow-up assessment can be completed; 5. The guardian signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Premature infants (gestational age < 34 weeks); 2. Complicated with neonatal respiratory distress syndrome, meconium aspiration syndrome, congenital pulmonary dysplasia, etc. 3. Complicated with persistent pulmonary hypertension or congenital heart disease that affects the pulmonary circulation; 4. Need immediate tracheal intubation and receive invasive mechanical ventilation after birth; 5. Automatically give up treatment or develop severe complications such as shock or sepsis during treatment; 6. Have incomplete imaging or clinical data, and cannot complete the main outcome assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The changes in lung ultrasound score (LUS) over time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total duration of respiratory support;Duration of non-invasive respiratory support;hospital stays; | — |
Countries
China
Contacts
The Second Affiliated hospital of Fujian Medical University