Glaucoma
Conditions
Interventions
Primary Glacuoma:N/A
Sponsors
Eye & ENT Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of primary angle-closure glaucoma (PACG) or primary open-angle glaucoma (POAG). Diagnosis criteria for PACG: presence of iris-tissue adhesion to the trabecular meshwork, intraocular pressure >= 21 mmHg, and accompanying definite glaucomatous optic neuropathy with corresponding visual field defects; diagnosis criteria for POAG: progressive optic nerve damage characterized by changes in the optic disc, retinal nerve fiber layer, or visual field, with open anterior chamber angle and no other diseases causing optic nerve alterations. 2. Age between 18 and 80 years.
Exclusion criteria
Exclusion criteria: 1.History of previous ocular trauma and intraocular surgery (excluding laser peripheral iridectomy and laser peripheral iridoplasty); 2.Secondary glaucoma; 3.Severe systemic diseases, such as uncontrolled diabetes; 4.Combined with retinal or optic nerve diseases, neovascular diseases, or other ocular diseases except for glaucoma and cataracts; 5.Long-term history of systemic or local hormone use.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure;Glaucoma Optical Coherence Tomography(OCT); | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Acuity;Refraction;Anterior Segment Photography;Retinal Photography;Central Visual Field;Ultrasound Biomicroscopy(UBM),questionnaire survey, etc.;Other parameters: Best-corrected visual acuity, slit-lamp examination, fundus examination, central corneal thickness, axial length measurement, gonioscopy, perimetry (Humphrey or Octopus), peripheral blood, tear fluid, iris tissue, trabecular meshwork tissue, aqueous humor; | — |
Countries
China
Contacts
Public ContactSun Xinghuai, Chen Yuhong
Eye & ENT Hospital of Fudan University
Outcome results
None listed