None
Conditions
Interventions
Youth group(18-44 years old):Using the improved Dixon sequential method, the initial dose of remifentanil besylate was set at 0.20mg/kg and the dose gradient was set at 0.01mg/kg based on pre experime
Middle aged group(45-59 years old):Using the improved Dixon sequential method, the initial dose of remifentanil besylate was set at 0.20mg/kg and the dose gradient was set at 0.01mg/kg based on pre ex
Elderly group(60-74 years old):Using the improved Dixon sequential method, the initial dose of remifentanil besylate was set at 0.20mg/kg and the dose gradient was set at 0.01mg/kg bas
Sponsors
Yan'an University Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 74 Years
Inclusion criteria
Inclusion criteria: 1.ASA classification I-II; 2.Age range: 18-74 years old, male or female not limited, BMI18-28kg/m^2; 3.Patients who plan to undergo general anesthesia surgery in our hospital; 4.Patients and their families sign informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with serious systemic diseases; 2.Individuals with contraindications or allergies to drugs related to this study; 3.Long term history of taking sedatives and analgesics; 4.Difficult airway patients;.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The drug dose at MOAA/S=0 minutes after administration of remifentanil during anesthesia induction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Mean arterial pressure;Pulse oximetry;EEG Bispectral Index;Eyelash reflex disappearance time;Time of disappearance of consciousness; | — |
Countries
China
Contacts
Public ContactLingxia Li
Yan'an University Affiliated Hospital
Outcome results
None listed