Inflammatory bowel disease-metabolic dysfunction-associated steatotic liver disease(IBD-MASLD)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: From October 2025 to October 2027, patients diagnosed with IBD in the gastroenterology department of the research unit.
Exclusion criteria
Exclusion criteria: 1. Excessive alcohol consumption (ethanol intake >=210 g/week for men and >=140 g/week for women); 2. Colitis due to other causes, including infectious enteritis (e.g., bacterial, amoebic, or schistosomal), drug-induced enteropathy, or radiation-induced colitis; 3. Steatotic liver disease attributable to other etiologies, including genotype 3 HCV infection, drug-induced steatosis, Wilson's disease, or malnutrition; 4. Hematologic disorders unsuitable for blood sampling; 5. Pregnancy (confirmed by serum ß-hCG testing), lactation, or women actively planning pregnancy; 6. Use of medications known to affect hematologic parameters or gut microbiota within one month prior to enrollment; 7. Pre-existing primary diseases of vital organs (heart, liver, kidney) or other severe conditions deemed by investigators to contraindicate participation; 8. Age <18 years, or lack/limitation of legal capacity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Controlled Attenuation Parameter;Liver Stiffness Measurement ; | — |
Secondary
| Measure | Time frame |
|---|---|
| General clinical data;Improved version of Mayo score;PRO questionnaire scoring scale;Metabolic risk assessment; | — |
Countries
China
Contacts
Longhua Hospital Shanghai University of Traditional Chinese Medicine