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Clinical Observation of Allogeneic Hematopoietic Stem Cell Transplantation in Children with High-Risk T-cell Acute Lymphoblastic Leukemia

Clinical Observation of Allogeneic Hematopoietic Stem Cell Transplantation in Children with High-Risk T-cell Acute Lymphoblastic Leukemia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117387
Enrollment
Unknown
Registered
2026-01-23
Start date
2017-02-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T-cell Acute Lymphoblastic Leukemia

Interventions

UCBT-Cla group:None
UCBT-Flu group:None
PBSCT-TBI group:None

Sponsors

Sun Yat-sen Memorial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1.Age 0-18 years; 2.Primary diagnosis of T-ALL with high-risk clinical classification; 3.Received induction and consolidation chemotherapy according to the SCCLG-ALL-2016 protocol prior to transplantation;

Exclusion criteria

Exclusion criteria: 1.Pediatric patients with other hematologic diseases undergoing hematopoietic stem cell transplantation or second transplantation;

Design outcomes

Primary

MeasureTime frame
Overall Survival;Transplant-Related Mortality;Relapse;Leukemia-Free Survival;—

Secondary

MeasureTime frame
Incidence of GVHD after transplantation;Hematopoietic reconstitution;Conditioning-related toxicities;—

Countries

China

Contacts

Public ContactWu Zhengzhou

Sun Yat-sen Memorial Hospital

wuzhzh28@mail.sysu.edu.cn+86 20 34070116

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026