Femoral shaft fracture
Conditions
Interventions
Group 1:Ropivacaine Hydrochloride 0.25%
Group 2:Bupivacaine Liposome 0.665%
Group 3:Bupivacaine Liposome 0.887%
Group 4:Bupivacaine Liposome 1.335%
Sponsors
Ethics Committee of the 960th Hospital of the Chinese People's Liberation Army
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age 18–85 years, no gender restriction 2. Diagnosed with unilateral femoral shaft fracture, scheduled for open reduction and internal fixation 3. Voluntarily agreed to participate in this study and signed written informed consent
Exclusion criteria
Exclusion criteria: Exclusion Criteria: 1.Patients with local infection at the puncture site; 2.Uncooperative patients; 3.Patients with cranial or cerebral injury; 4.Patients with impaired consciousness; 5.Patients with severe impairment of hepatic or renal function; 6.Patients allergic to local anesthetics; 7.Patients complicated by shock; 8.Women who are pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative VAS Pain Scores at Rest and during Movement within 96 Hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative hemodynamic parameters and total dose of remifentanil administered;Assessment of quadriceps muscle strength using the postoperative Oxford Scale (0-5).; | — |
Countries
China
Contacts
Public ContactGong Jing
The 960th Hospital of the Chinese People's Liberation Army Joint Logistics Support Force
Outcome results
None listed