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Assessing cerebral cortical responses to maternal voice in children during emergence from general anesthesia: A functional near-infrared spectroscopy (fNIRS) study

Assessing cerebral cortical responses to maternal voice in children during emergence from general anesthesia: A functional near-infrared spectroscopy (fNIRS) study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117350
Enrollment
Unknown
Registered
2026-01-22
Start date
2026-01-30
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Mother Voice Group:During the child's anesthesia recovery period, the recorded content played was a voice Biological mother's voice group: complete in emotion and semantics. The recorded content is a
AI Female Voice Group:Female AI voice group: retain the semantic content but strip away emotional factors. The recorded content remains "Baby, wake up, mom is here. We've finished the surgery, mom is
Mother's reverse sequence voice group:Reverse order group: The recording was still made by the mother herself, "Baby, wake up, mom is here. We've finished the surgery, mom is here to pick you up." Aft
Control group:There is no special sound stimulation.

Sponsors

The First Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1) Children, aged 5-12 years; 2) ASA classification I or II; 3) Scheduled for tonsillectomy or adenoidectomy; 4) Parents agree to participate in the study and sign the informed consent form

Exclusion criteria

Exclusion criteria: (1) Left-handedness; (2) Non-native Chinese speakers; (3) Deafness or hearing impairment; (4) History of neurological or psychiatric disorders or family history of hereditary neuropsychiatric diseases; (5) Developmental language or cognitive impairment; (6) History of sleep disorders; (7) Severe congenital diseases, such as cardiovascular diseases, respiratory diseases, etc.; (8) Maternal aphasia or absence. (9) Major life changes occurring within one month before the surgery (e.g., parental divorce or school transfer)

Design outcomes

Primary

MeasureTime frame
The incidence and duration of delirium in children within 3 days after the operation;

Secondary

MeasureTime frame
Dynamic activation indicators of brain regions;The incidence rate of EA;The incidence rate of failed tracheal extubation after the first body movement;Sleep quality;Core Indicators of Heart Rate Variability (HRV) (SDNN, RMSSD, LF/HF Ratio);

Countries

China

Contacts

Public ContactJingjin Li

The First Affiliated Hospital of Nanjing Medical University

crystalni@qq.com+86 151 0516 7727

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026