Elevated PSA
Conditions
Interventions
Group E:The dose of oliceridine for each patient was determined using a modified Dixon sequential method
Group M:The dose of oliceridine for each patient was determined using a modified Dixon sequential method
Sponsors
Affiliated Hospital of Jiangnan University
Eligibility
Sex/Gender
Male
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1: Older men planned for transperineal prostate biopsy under ultrasound guide; 2: Age >= 65 years; 3: BMI 18. 5~20. 0 kg/m^2; 4: ASA ?~?.
Exclusion criteria
Exclusion criteria: 1: use of sedatives or analgesics within 24 h before surgery; 2: difficult airway (modified Mallampati grade IV); 3: communication or cognitive impairment; 4: allergy to study drugs; 5: severe cardiovascular, pulmonary, hepatic, or renal dysfunction;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oliceridine dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative adverse reactions such as respiratory depression,hypotension and bradycardia;Satisfaction score of patients, anesthesiologists and surgeons;Occurrence of postoperative adverse reactions, such as dizziness and nausea/vomiting; | — |
Countries
China
Contacts
Public ContactZhu Yunxia
Affiliated Hospital of Jiangnan University
Outcome results
None listed