Spinal Anaesthesia-induced Hypotension
Conditions
Interventions
Phenylephrine group:The parturient received a continuous intravenous infusion of phenylephrine at a rate of 0.5 µg/(kg·min) immediately following spinal anesthesia, which was discontinued upon deliver
Left lateral wedge position pad group:Following the administration of spinal anesthesia, a left lateral tilt wedge positioning pad was placed under the right lumbar/buttock region of the parturient an
Phenylephrine combined with left lateral wedge position pad group:Following the administration of spinal anesthesia, the parturient received a continuous intravenous infusion of phenylephrine at 0.5 µ
Blank control group:Following spinal anesthesia, the parturient was placed in a supine position without any prophylactic intervention. Standard maternal vital signs were monitored continuously. If spi
Sponsors
Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Singleton term pregnancy scheduled for elective cesarean delivery, with maternal age ranging from 20 to 45 years. 2. Absence of contraindications to neuraxial anesthesia.
Exclusion criteria
Exclusion criteria: 1.Gestational age 170 cm, or body weight 90 kg. 4.Patient or family member declines to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of hypotension from anesthesia induction to fetal delivery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Other maternal observation indicators: heart rate, fluid intake, blood loss, urine output, and incidence of adverse reactions (including nausea, vomiting, dizziness, etc.).;Maternal baseline characteristics: body mass index (BMI), age, gestational week and parity, preoperative blood pressure (BP) and heart rate (HR) baseline, preoperative fasting duration, etc.;Newborn observation indicators: birth weight, 1-minute and 5-minute Apgar scores, umbilical artery blood parameters (blood gas analysis including pH, PO2, PCO2, base excess, and lactate levels), and rate of neonatal transfer to the NICU.; | — |
Countries
China
Contacts
Public ContactYuan Hongmei
Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital
Outcome results
None listed