acute kidney injury
Conditions
Interventions
Observation group:None
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Patients hospitalised and treated with vancomycin between 2020-2023. (2) Vancomycin courses of 5 days or more, with vancomycin trough concentrations measured at least once on days 3-7 of treatment. (3) Signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with haemodialysis, peritoneal dialysis, CRRT; (2) Patients with nephrectomy, renal transplantation, single kidney, uremia. (3) Vancomycin administration is not intravenous (including 24h intravenous pump). (4) Patients who have had two/multiple applications of vancomycin within one year taking only the first vancomycin. (5) Failure to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between vancomycin dose and nephrotoxicity;CCorrelation between vancomycin trough concentration and nephrotoxicity; | — |
Secondary
| Measure | Time frame |
|---|---|
| 30-day mortality;90-day mortality; | — |
Countries
China
Contacts
Public ContactLi Hongxia
Chinese PLA General Hospital
Outcome results
None listed