Peritoneal Dialysis
Conditions
Interventions
Experimental Group: Niaoduqing Granules +peritoneal dialysis (PD)
Control Group:peritoneal dialysis (PD)
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18–70 years old, no gender limitation. 2. Indication: Undergoing peritoneal dialysis due to end-stage renal disease (ESRD). 3. Residual Renal Function: Baseline residual renal function = 2 ml/min/1.73 m² at the initiation of dialysis. 4. Informed Consent: Willing to participate in this study and has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Having other severe primary diseases such as congestive heart failure, chronic obstructive pulmonary disease (COPD), myocardial infarction, liver cirrhosis, and active malignant tumors. 2. Poor patient compliance and inability to cooperate with the study. 3. Uncontrolled hypertension (systolic blood pressure [SBP] = 160 mmHg and/or diastolic blood pressure [DBP] = 100 mmHg); symptomatic hypotension or systolic blood pressure < 90 mmHg at screening. 4. Inability to receive peritoneal dialysis due to various reasons such as abdominal surgery and intestinal adhesion. 5. A history of kidney transplantation or maintenance hemodialysis. 6. Pregnant or lactating women, or subjects allergic to the study drug. 7. Complicated with mental illness or unable to complete follow-up. 8. Participation in other clinical trials of drugs or medical devices within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| KT/V; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of decline in residual renal function;Capacity load indicators: time to anuria, extracellular water (ECW) changes; | — |
Countries
China
Contacts
Public ContactYin Yao
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technolog
Outcome results
None listed