Parkinson's disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for PD patients: (1) Diagnosed with primary Parkinson's disease by a specialist according to the MDS 2015 diagnostic criteria, aged 55-80 years; (2) Hoehn-Yahr (H-Y) disease stage 1-4; (3) Receiving Parkinson's disease medication with stable condition, and no adjustment to the medication regimen within 3 months after enrollment; (4) No significant cognitive impairment (MoCA >= 20 points); (5) Voluntary participation and signed informed consent. 2. Inclusion criteria for healthy control group: (1) Aged 55-80 years; (2) Able to understand and respond to instructions given in the study.
Exclusion criteria
Exclusion criteria: 1. Patients with cognitive impairment (MoCA <20); 2. Patients with a history of lung surgery, recent respiratory infection, or other lung diseases confirmed by imaging; 3. Patients with unstable cardiovascular disease; 4. Patients with mental illness or other serious illnesses.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximum Expiratory Pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung Volumes;The Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Score;Maximal Inspiratory Pressure;Parkinson's Disease Questionnaire (PDQ-39);6-minute walk test;Thoracic Mobility;Vital Capacity;Maximum Voluntary Ventilation;Diaphragmatic Ultrasound;Respiratory Muscle Surface Electromyography; | — |
Countries
China
Contacts
Shanghai Yangzhi rehabilitation hospital