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An Observational Study on the Association between PET/MR Imaging Features and Prognosis in Brain Injury Patients Complicated with Acute Consciousness Disorders

An Observational Study on the Association between PET/MR Imaging Features and Prognosis in Brain Injury Patients Complicated with Acute Consciousness Disorders

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117289
Enrollment
Unknown
Registered
2026-01-22
Start date
2026-02-15
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic brain injury

Interventions

Healthy control group:None

Sponsors

Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria for the brain injury group: (1) Patients with brain injury who were previously treated at our hospital and have completed PET/MR scans; (2) Diagnosed with traumatic brain injury or hemorrhagic stroke; (3) Aged 18-80 years; (4) Minimum GCS score of 3-12 on the day of onset; (5) PET/MR examination conducted within 28 days of onset; (6) Received more than 1 month of hyperbaric oxygen therapy and multisensory stimulation after discharge; (7) Completed follow-up for more than 6 months. 2. Inclusion criteria for the healthy population group: (1) Aged 18-80 years; (2) Provided informed consent and cooperated with examinations.

Exclusion criteria

Exclusion criteria: 1. Exclusion criteria for the brain injury group: (1) Death during hospitalization; (2) Refusal to participate in this study; (3) History of malignant tumors; (4) History of neurological or psychiatric disorders; (5) Ineligible PET/MR imaging data. 2. Exclusion criteria for the healthy control group: (1) History of neurological diseases; (2) Presence of claustrophobia.

Design outcomes

Primary

MeasureTime frame
The state of consciousness;Cognitive function;

Secondary

MeasureTime frame
Complication of hydrocephalus;Complication of epilepsy;Neurological functional;

Countries

China

Contacts

Public ContactXi Wang

Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University)

xiwang_199112@163.com+86 25 68303064

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026