Gallbladder stones, acute cholecystitis, chronic cholecystitis, gallbladder polyps
Conditions
Interventions
Remimazolam Group:Induction and Maintenance of Remimazolam Benzenesulfonate
Sponsors
Baotou Central Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Age >= 60 years old (2) The surgical indications are clear, laparoscopic cholecystectomy is performed, and it also meets the indications for general anesthesia; (3) ASA grade I-III of the American Society of Anesthesiologists; (4) BMI 18.5 - 30 kg/m^2; (5) Informed consent, voluntarily participating in this trial, and signing the informed consent form.
Exclusion criteria
Exclusion criteria: (1) The subjects explicitly refused to participate in this study; (2) Those with a history of severe heart, brain, lung, liver, kidney and metabolic diseases; (3) Those with a previous history of abnormal surgical anesthesia recovery; (4) Electrocardiogram indicates: heart rate 180 mmHg and/or diastolic blood pressure > 110 mmHg, or hypotensive patients with < 90/60 mmHg; (7) Those with neurological and muscular system diseases, mental disorders and extremely poor coagulation function; (8) Those suspected of abusing anesthetic analgesics or sedatives, and those with a history of using tropisetron; (9) Those who are predicted to have or have had difficult airways; (10) Subjects considered not suitable to participate in this study by the researchers;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bispectral index;Anesthesia induction time;Time to loss of eyelash reflex during anesthesia induction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean Arterial Pressure;Heart rate;Blood oxygen saturation;End-tidal carbon dioxide partial pressure;Incidence of adverse reactions;Use of Vasoactive Drugs;Time to recovery from anesthesia;Sedation-Agitation Rating;Visual Simulation Score;Postoperative cognitive function; | — |
Countries
China
Contacts
Public ContactBai Shuancheng
Baotou Central Hospital
Outcome results
None listed