Myocardial Injury after Non-cardiac Surgery (MINS) in elderly patients undergoing gastrointestinal tumor surgery
Conditions
Interventions
Experimental Group (Intelligent Warming Strategy Group):Intraoperative intelligent active warming measures were implemented
based on real-time temperature feedback from the tympanic membrane temperature sensor, the warming device was dynamically regulated to maintain a target body temperature of 36.8°C, with an upper limit
Control group (routine warming strategy group):During surgery, passive warming measures (covering with blankets) should be initiated first. If the patients intraoperative temperature drops to 35.5°C,
Sponsors
The Third Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years; 2. Patients undergoing elective gastrointestinal tumor resection under general anesthesia; 3. Patients with an anticipated surgical duration exceeding 2 hours; 4. Subjects who are willing to participate and have signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with a documented history of allergy to the trial device or related materials; 2. Patients with an American Society of Anesthesiologists (ASA) physical status classification of >=IV; 3. Patients who are unconscious and unable to cooperate with the conduct of this study; 4. Patients with less than 50% of body surface area available for active warming measures; 5. Patients with moderate to severe obesity (BMI >=30 kg/m²); 6. Patients with a preoperative core temperature (measured at the tympanic membrane) exceeding 37.5°C; 7. Patients with a preoperative diagnosis of thyroid dysfunction, including but not limited to hyperthyroidism or hypothyroidism; 8. Patients with severe hepatic dysfunction (Child-Pugh Class C); 9. Patients with concomitant intracranial tumors or other conditions potentially affecting thermoregulation; 10. Patients with severe anemia (Hb < 60 g/L) at baseline; 11. Patients deemed ineligible for this study by the investigator for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Myocardial Injury after Non-cardiac Surgery (MINS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative surgical site infection (SSI);Intraoperative blood product transfusion rate and total transfusion volume;Duration of intraoperative body temperature <36.0°C;Emergence delirium;Delayed emergence;Postoperative shivering; | — |
Countries
China
Contacts
Public ContactLiao Qin/ Ou Yangwen
The Third Xiangya Hospital of Central South University
Outcome results
None listed