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Exploration of the efficacy and safety of suldaparin sodium vs. low molecular weight heparin sodium in preventing thrombotic events during the perioperative period of liver transplantation: A randomized controlled study

Exploration of the efficacy and safety of suldaparin sodium vs. low molecular weight heparin sodium in preventing thrombotic events during the perioperative period of liver transplantation: A randomized controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117233
Enrollment
Unknown
Registered
2026-01-21
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver cirrhosis, liver cancer, etc

Interventions

Suldaparilla sodium group:Suldaparilla sodium is subcutaneously injected once, one vial per day
Low molecular weight heparin group:Low molecular weight heparin is subcutaneously injected once, one vial per day

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age > 18 and < 70 years old, gender not limited; 2. Liver transplant recipients with high-risk factors for thrombotic events; 3. Patients without deep vein thrombosis or pulmonary embolism before the operation.

Exclusion criteria

Exclusion criteria: 1. Anticoagulant drugs were used for treatment before enrollment; 2. Patients with hereditary coagulation dysfunction; 3. Contraindications for the use of low-molecular-weight heparin/suldaparinol sodium: patients with severe organ bleeding (such as obvious abdominal hemorrhage or cerebrovascular accident, etc.), hemorrhagic diseases or bleeding tendency, and those allergic to low-molecular-weight heparin/suldaparinol sodium, etc., who are determined by a surgeon to be unable to use anticoagulation; 4. Patients with severe renal insufficiency; 5. The researchers believe that the current condition of the subjects is not suitable for participating in this study.

Design outcomes

Secondary

MeasureTime frame
The incidence of postoperative bleeding;

Primary

MeasureTime frame
The incidence of thrombotic events within one month after the operation;All-cause mortality within one month after surgery;

Countries

China

Contacts

Public ContactYang Jiaying

West China Hospital, Sichuan University

doctoryjy@scu.edu.cn+86 189 8060 2047

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026