Hypertrophic cardiomyopathy
Conditions
Interventions
experimental group: hypertrophic cardiomyopathy:NA
Control group:NA
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: HCM inclusion criteria: 1. The maximum wall thickness of any one or multiple myocardial segments of the left ventricle at the end of diastole is = 15 mm (or = 13 mm for patients with a clear family history), and it cannot be explained by other diseases (such as hypertension, aortic stenosis, etc.). 2. Diagnostic criteria for apical HCM: The ratio of apical/basal wall thickness is >1.0, and there are typical electrocardiogram (ECG) abnormalities - a giant inverted T wave. Inclusion criteria for the control group: no history or symptoms of cardiovascular disease. The CMR examination showed that the heart structure and function were completely normal.
Exclusion criteria
Exclusion criteria: Exclusion criteria for HCM: Age 140 mmHg or diastolic blood pressure > 90 mmHg); patients with severe renal insufficiency (eGFR < 30 ml/min/1.73m²); previous cardiac surgery history before CMR examination: such as history of septal myotomy or alcoholic septal ablation, permanent pacemaker or ICD implantation; incomplete CMR examination or image impact assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wall thickness, atrioventricular coupling index, LGE, ventricular and atrial strain, T1, T2; | — |
Secondary
| Measure | Time frame |
|---|---|
| HDF and PV loop were used to evaluate hemodynamic changes; | — |
Countries
China
Contacts
Public ContactLiling Long
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed