Mycoplasma pneumoniae pneumonia
Conditions
Interventions
children with MPP(experimental group):NA
children with bronchial foreign bodies (control group):NA
Sponsors
Shaoxing People’s Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The diagnosis of Mycoplasma pneumoniae pneumonia (MPP) conforms to the diagnostic criteria specified in China's Guidelines for the Diagnosis and Treatment of Mycoplasma pneumoniae Pneumonia in Children (2023 Edition). 2. Flexible bronchoscopy examination complies with the requirements of Guidelines for Flexible Bronchoscopy in Pediatrics of China (2018 Edition) and Guidelines for the Diagnosis and Treatment of Mycoplasma pneumoniae Pneumonia in Children (2023 Edition), with strict adherence to the indications and contraindications for bronchoscopy. 3. Children with bronchial foreign bodies meet the criteria in Expert Consensus on the Diagnosis and Treatment of Tracheobronchial Foreign Bodies in Children of China. 4. Diagnosis of airway hyperresponsiveness: Based on Respiratory Medicine and Pulmonology: Presence of clinical symptoms such as cough, wheezing, and dyspnea; Auscultation of wheezes in the lungs.
Exclusion criteria
Exclusion criteria: 1. Children with Mycoplasma pneumoniae pneumonia complicated by infection with other pathogens such as bacteria, viruses, or fungi; 2. Those with a history of recurrent wheezing; 3. Children with bronchial foreign bodies who are excluded from having concurrent pathogen infections; 4. Those with severe underlying diseases such as basic diseases of important organs including the heart, liver, brain, and kidneys, or those with autoimmune diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OutcomeExpression level of miR-21; | — |
Secondary
| Measure | Time frame |
|---|---|
| Interleukin-6;Transforming Growth Factor-beta;Interleukin-10;Interleukin-2;Interleukin-17; | — |
Countries
China
Contacts
Public ContactXiaoqun Liu
Shaoxing People’s Hospital
Outcome results
None listed