Gastric cancer
Conditions
Interventions
Observation group for gastric cancer treatment:None
Sponsors
Shanghai East Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Age >= 18 years old; (2) Locally advanced or metastatic gastric or gastroesophageal junction epithelial malignancies that are not resectable, confirmed by histological or cytological examination; (3) Tumor tissue HER2 expression is confirmed by immunohistochemical staining (immunohistochemistry, IHC) as HER2 >= 1+, and/or positive by fluorescence in situ hybridization technique (fluorescence in situ hybridization, FISH); (4) Received HER2-targeted therapy from June 1, 2016 to May 31, 2023; (5) Has follow-up information.
Exclusion criteria
Exclusion criteria: 1. Suffering from other malignant tumors simultaneously; 2. No tumor assessment was conducted after HER2-targeted treatment; 3. Incomplete clinical and pathological data (including but not limited to the absence of previous treatment information, tumor assessment information after anti-HER2 treatment, etc.); 4. Patients who received radiotherapy for target lesions during HER2-targeted treatment; 5. Other situations that the researchers consider not suitable for inclusion in the analysis, such as inconsistent tumor assessment information before and after, which may affect the assessment of the study endpoint.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-free survival period; | — |
Countries
China
Contacts
Public ContactXiaoxiao Ge
Shanghai East Hospital
Outcome results
None listed