The Effects of different mechanical ventilation modes on intracranial pressure in obesity patients undergoing laparoscopic surgery under Trendelenburg position

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600117222

Enrollment

Unknown

Registered

2026-01-21

Start date

2026-02-01

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesity patients undergoing laparoscopic surgery under Trendelenburg position

Interventions

VCV group:volume controlled ventilation mode

PCV-VG group:pressure controlled ventilation-volume guaranteed mode

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA I-II; 18-65 years;BMI>=30kg/m^2; Pneumoperitoneum and the Trendelenburg position are expected to last for more than 1 hour.

Exclusion criteria

Exclusion criteria: history of ocular diseases; history of ocular surgery or trauma; history of cerebrovascular diseases or any neurological disorders; history of abdominal surgery; history of pulmonary diseases.

Design outcomes

Primary

Measure	Time frame
optic nerve sheath diameter;	—

Secondary

Measure	Time frame
SpO2;Heart rate;blood pressure;peak pressure;rate of nausing and vomiting;	—

Countries

China

Contacts

Public ContactWang Liangrong

The First Affiliated Hospital of Wenzhou Medical University

arerong1984@126.com+86 135 8788 4540

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026