Postoperative delirium
Conditions
Interventions
Intervention group:The intervention group, on the basis of conventional anesthesia management, set an additional intervention target of rSO2 not less than 10% of the baseline value or an absolute valu
Adjust the position of the head and neck to avoid obstruction of jugular venous return. 2. Optimize oxygenation: Gradually increase FIO2 to 100% to ensure maximum brain oxygen supply
3. Adjust the respiratory parameters, setting the respiratory rate to 10-12 times per minute or reducing the tidal volume to 6ml/kg, and increasing the partial pressure of carbon dioxide to 45-50 MMHG
Control group:The control group was monitored for rSO2 throughout the operation using a brain/body oxygen meter, but only received conventional perioperative anesthesia management. The management goal
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. ASA status I-III; 2. Age >=60 years old; 3. Be conscious and capable of independent thinking; 4. Patients scheduled for spinal surgery (prone position); 5. Agree to participate in the trial.
Exclusion criteria
Exclusion criteria: 1. The preoperative Mini-Mental State Examination (MMES) score was less than 24 points; 2. There is a history of surgery, trauma, lesion and infection on the forehead; 3. Combined with serious diseases, including severe liver and kidney function damage, cardiovascular and cerebrovascular diseases, etc. Poor control of diabetes and hypertension; 4. Poor compliance, making it difficult to cooperate with treatment and follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of postoperative cognitive dysfunction;Postoperative pain score;Dosage of anesthetic drugs;Length of hospital stay; | — |
Countries
China
Contacts
Public ContactBin Wang
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed