Progressive corneal thinning, abnormal collagen fibril architecture, and progressively increasing curvature lead to irregular astigmatism and severe visual deterioration.
Conditions
Interventions
Observation group:None
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with ectatic corneal disorders undergoing CXL for the first time at any age. 2.Postoperative follow-up of at least 1 year, with the last visit >=5 years after surgery.
Exclusion criteria
Exclusion criteria: 1.Prior corneal procedures (e.g., intrastromal corneal ring segments, excluding laser corneal refractive surgery), intraocular surgery, or glaucoma surgery. 2.Comorbid glaucoma; 3.Severe infection; 4.Comorbid autoimmune disease;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative maximum keratometry (Kmax); | — |
Secondary
| Measure | Time frame |
|---|---|
| Other corneal topographic parameters;Visual function parameters;Disease progression rate; | — |
Countries
China
Contacts
Public ContactZhang Jia
Eye Hospital, Wenzhou Medical University
Outcome results
None listed