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ZBED5-AS1: A New Clue for the Diagnostic and Metastatic Mechanisms in Lung Adenocarcinoma

Auxiliary diagnostic value of long non-coding RNA ZBED5-AS1 in lung adenocarcinoma and its mechanism of promoting lung adenocarcinoma metastasis by regulating miR-524-5p/GPI axis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117211
Enrollment
Unknown
Registered
2026-01-21
Start date
2026-01-21
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Adenocarcinoma

Interventions

Sponsors

The First Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria for patients with lung adenocarcinoma: (1) Confirmed as primary lung adenocarcinoma by pathology and imaging; (2) First-time diagnosis, with the patient having not undergone any chemotherapy or surgical treatment. 2. Inclusion criteria for healthy subjects: Normal physiological indicators.

Exclusion criteria

Exclusion criteria: 1. Exclusion criteria for lung adenocarcinoma patients: (1) Severe dysfunction of the heart, liver, or kidneys; (2) Severe autoimmune diseases; (3) History of other malignant tumors. 2. Exclusion criteria for healthy subjects: (1) History of lung adenocarcinoma or other malignancies; (2) Severe dysfunction of the heart, liver, or kidneys, or other major diseases.

Design outcomes

Primary

MeasureTime frame
ZBED5-AS1 mRNA expression;Area Under the Receiver Operating Characteristic Curve?Specificity?Sensitivity;

Secondary

MeasureTime frame
Clinicopathological parameters of lung adenocarcinoma tissue (e.g., gender, age, smoking history);

Countries

China

Contacts

Public ContactJiang Feng, Wang Yumin

The First Affiliated Hospital of Wenzhou Medical University

jiangfeng@wmu.edu.cn+86 577 5779023

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026