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The role and mechanism of gut microbiota in oxaliplatin-induced peripheral neuropathy

The role and mechanism of gut microbiota in oxaliplatin-induced peripheral neuropathy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117203
Enrollment
Unknown
Registered
2026-01-21
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

OIPN negative group:None
OIPN positive group:None

Sponsors

Tongde Hospital of Zhejiang Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.18-80 years old with pathologically confirmed colorectal cancer who have undergone radical surgery; 2. No distant metastasis; 3. Use a chemotherapy regimen containing oxaliplatin; 4. Able to independently complete emotional and follow-up tasks.

Exclusion criteria

Exclusion criteria: 1. Pregnant or breastfeeding period; 2. Accompanied by serious systemic diseases; 3. Have used antibiotics or probiotic products in the past 3 weeks; 4. Have used non body preserving drugs, glucocorticoids, and drugs containing salicylic acid components in the past 3 months.

Design outcomes

Primary

MeasureTime frame
The main symptoms of the patient;—

Countries

China

Contacts

Public ContactWu Jinfeng

Tongde Hospital of Zhejiang Province

siri0907@163.com+86 571 89972433

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026