Acute ST-segment elevation myocardial infarction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Meets the diagnostic criteria for acute ST-segment elevation myocardial infarction (STEMI) as defined in the Fourth Universal Definition of Myocardial Infarction (2018), and meets the indications for emergent PCI in STEMI patients as stated in the 2024 Society for Cardiovascular Angiography and Interventions (SCAI) Expert Consensus Statement on the Management of STEMI Patients Undergoing Primary PCI; 2.Undergoes PCI within 12 hours of symptom onset; 3.Completes cardiac magnetic resonance (CMR) examination on postoperative day 5; 4.Age >= 18 years; 5.Good compliance; 6.CMR image quality grade I; 7.The participant or their legal guardian voluntarily agrees to participate and signs written informed consent.
Exclusion criteria
Exclusion criteria: 1.Prior history of myocardial infarction and having received emergency thrombolysis, percutaneous coronary intervention, or coronary artery bypass grafting (CABG); 2.Severe, uncorrectable arrhythmia; 3.History of congenital heart disease, hypertrophic cardiomyopathy, dilated cardiomyopathy, valvular heart disease, or other structural heart diseases; 4.Presence of aortic dissection; 5.Severe hepatic or renal dysfunction; 6.Concomitant hematologic disorders or infectious diseases; 7.Allergy to contrast agents; 8.Malignant tumors; 9.Psychiatric disorders or intellectual disability resulting in inability to cooperate; 10.Contraindications to MRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sudden cardiac death (SCD) and SCD-related malignant ventricular arrhythmic events (composite endpoint); | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart failure rehospitalization;Major adverse cardiovascular events (MACE); | — |
Countries
China
Contacts
Huizhou Third People's Hospital