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Using follow-up cardiac MRI after PCI for STEMI to predict the risk of sudden cardiac death: a prospective cohort study

Prognostic value of longitudinal cardiac MRI parameters at different time points after PCI for acute ST-segment elevation myocardial infarction in predicting sudden cardiac death: a prospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117188
Enrollment
Unknown
Registered
2026-01-21
Start date
2026-01-31
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ST-segment elevation myocardial infarction

Interventions

Observation group:None

Sponsors

Huizhou Third People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Meets the diagnostic criteria for acute ST-segment elevation myocardial infarction (STEMI) as defined in the Fourth Universal Definition of Myocardial Infarction (2018), and meets the indications for emergent PCI in STEMI patients as stated in the 2024 Society for Cardiovascular Angiography and Interventions (SCAI) Expert Consensus Statement on the Management of STEMI Patients Undergoing Primary PCI; 2.Undergoes PCI within 12 hours of symptom onset; 3.Completes cardiac magnetic resonance (CMR) examination on postoperative day 5; 4.Age >= 18 years; 5.Good compliance; 6.CMR image quality grade I; 7.The participant or their legal guardian voluntarily agrees to participate and signs written informed consent.

Exclusion criteria

Exclusion criteria: 1.Prior history of myocardial infarction and having received emergency thrombolysis, percutaneous coronary intervention, or coronary artery bypass grafting (CABG); 2.Severe, uncorrectable arrhythmia; 3.History of congenital heart disease, hypertrophic cardiomyopathy, dilated cardiomyopathy, valvular heart disease, or other structural heart diseases; 4.Presence of aortic dissection; 5.Severe hepatic or renal dysfunction; 6.Concomitant hematologic disorders or infectious diseases; 7.Allergy to contrast agents; 8.Malignant tumors; 9.Psychiatric disorders or intellectual disability resulting in inability to cooperate; 10.Contraindications to MRI.

Design outcomes

Primary

MeasureTime frame
Sudden cardiac death (SCD) and SCD-related malignant ventricular arrhythmic events (composite endpoint);

Secondary

MeasureTime frame
Heart failure rehospitalization;Major adverse cardiovascular events (MACE);

Countries

China

Contacts

Public ContactYang Fei

Huizhou Third People's Hospital

15118970116@139.com+86 752 2359232

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026