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Optimizing Pulp Management in Autotransplantation of Mature Third Molars: A three-arm randomized controlled trial

Optimizing Pulp Management in Autotransplantation of Mature Third Molars: A three-arm randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117174
Enrollment
Unknown
Registered
2026-01-20
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impacted tooth

Interventions

Root-End Resection, RER:Autotransplantation with intraoperative root-end resection
Apical Surgery, AS:Autotransplantation with intraoperative apical surgery and retrograde filling
Postoperative Root Canal Therapy,PRCT:Autotransplantation with postoperative root canal therapy

Sponsors

The second affiliated hospital of Zhejiang University school of medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-40 years; 2. Requires extraction of a non-restorable first or second molar and possesses a fully developed, morphologically healthy third molar; 3. Has signed the informed consent form;

Exclusion criteria

Exclusion criteria: 1. Presence of acute infection or insufficient bone volume at the recipient site; 2. Donor tooth presents with caries, periapical disease, or periodontal disease; 3. Has uncontrolled systemic disease, is pregnant or lactating, or smokes >10 cigarettes per day; 4. Unable to comply with long-term follow-up;

Design outcomes

Primary

MeasureTime frame
Incidence of Inflammatory Root Resorption;Survival Rate;Success Rate;

Secondary

MeasureTime frame
Postoperative pain level;Incidence of adverse events;Pulp revascularization(RER);

Countries

China

Contacts

Public ContactXia Jiajia

The second affiliated hospital of Zhejiang University school of medicine

jackey-xia@zju.edu.cn+86 571 89713387

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026