Postoperative analgesia after total knee arthroplasty
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 50 to 80 years old; 2. Scheduled for primary unilateral total knee arthroplasty; 3. Diagnosed with primary knee osteoarthritis (Kellgren-Lawrence grade ?-?) by imaging and clinical examination; 4. American Society of Anesthesiologists (ASA) physical status classification ?-?; 5. Conscious, with good communication skills, able to understand the research content and cooperate in completing the evaluation; 6. Voluntarily participate and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with hypersensitivity to local anesthetics; 2. Patients with coagulation disorders (platelet count 1.5); 3. Patients with severe cardiac, pulmonary, hepatic, or renal dysfunction (NYHA class ?–? cardiac function, forced expiratory volume in one second (FEV1) < 50% of predicted value, Child-Pugh class C liver function, or estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73m^2); 4. Patients with a history of mental illness or cognitive impairment who are unable to cooperate with the evaluation; 5. Patients with a previous history of ipsilateral knee joint surgery; 6. Pregnant or lactating women; 7. Patients who refuse to participate in this study or are unable to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of patients with active knee flexion angle >= 90° within 24 hours after surgery;Proportion of patients able to walk >= 10 meters with assistance within 48 hours after surgery;Postoperative muscle strength of the quadriceps, ankle dorsiflexors, and ankle plantar flexors;Patient satisfaction score;Adverse reactions within 48 hours after surgery; | — |
Countries
China
Contacts
Zibo Traditional Chinese Medicine Hospital