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The effects and underlying mechanism of adipokines and Hepatokines on lower extremity arterial disease of type 2 diabetes mellitus

The effects and underlying mechanism of adipokines and hepatokines on lower extremity arterial disease of type 2 diabetes mellitus

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117140
Enrollment
Unknown
Registered
2026-01-20
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lower extremity arterial disease of type 2 diabetes mellitus

Interventions

Normal glucose metabolism:N/A
Patient with type 2 diabetes:N/A
Patient with type 2 diabetes, patients with diabetic LEAD:N/A

Sponsors

Army Medical Center of PLA
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.The clinical case data are complete; 2.People with normal glucose metabolism: No underlying diseases such as diabetes, hypertension, tumors, or kidney diseases; 3.Patients with type 2 diabetes, including both patients who have been diagnosed previously and those newly diagnosed upon admission; 4.Patients with diabetic LEAD: Patients with type 2 diabetes who have obvious intermittent claudication, rest pain, ulcers, gangrene or an ABI value less than 0.9 meet the diagnostic criteria for diabetic lower extremity vascular disease.

Exclusion criteria

Exclusion criteria: 1.Type 1 diabetes, secondary diabetes, patients with severe liver or kidney dysfunction, and those with cardiac function grade III or above; 2.The acute complications of diabetes (including DKA, HHS, lactic acidosis); 3.Those with malignant tumors; 4.Missing of important data;

Design outcomes

Primary

MeasureTime frame
Changes in fat factors and hepatocyte factors;

Countries

China

Contacts

Public ContactZhencheng Yan

Army Medical Center of PLA

zhenchengyan@sina.com+86 23 6872 9687

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026