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Association Analysis of Blood Microbiome (2bRAD-M) and Metabolomic Characteristics in Patients with Atherosclerotic Cardiovascular Disease

Association Analysis of Blood Microbiome (2bRAD-M) and Metabolomic Characteristics in Patients with Atherosclerotic Cardiovascular Disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117130
Enrollment
Unknown
Registered
2026-01-20
Start date
2026-01-20
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atherosclerotic cardiovascular disease

Interventions

ASCVD case group:None
Healthy control group:None

Sponsors

Qingdao Traditional Chinese Medicine Hospital (Qingdao Hiser Hospital Affiliated to Qingdao University)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 95 Years

Inclusion criteria

Inclusion criteria: (1) Diagnostic Confirmation: Subjects meeting the diagnostic criteria for healthy volunteers or ASCVD, as confirmed by professional physicians through inpatient medical records. (2) Complete Medical Archives: Possession of comprehensive and traceable medical records, including inpatient, outpatient, or epidemiological data, along with medication history and follow-up records. (3) Qualified Specimens: Availability of qualified blood samples (whole blood and plasma) stored at -80°C. (4) Informed Consent: Participants who voluntarily agreed to join the study and provided written informed consent.

Exclusion criteria

Exclusion criteria: 1. Systemic diseases with intrinsic inflammatory response (such as inflammatory bowel disease, systemic lupus erythematosus, etc.); 2. Vegetarians or people with irregular diet and serious eating behavior disorders; 3. Chronic anti-inflammatory therapy with steroids and/or non-steroidal anti-inflammatory drugs or prior antibiotic therapy within the past 3 months; 4. Individuals with uncontrolled alcoholism or drug abuse; 5. Patients who have participated in other clinical trials within the past 3 months.

Design outcomes

Primary

MeasureTime frame
Blood microbial sequencing;

Secondary

MeasureTime frame
Metabolomic profiling;

Countries

China

Contacts

Public ContactTing Jiang

Qingdao Traditional Chinese Medicine Hospital (Qingdao Hiser Hospital Affiliated to Qingdao University)

jiangting@qdu.edu.cn+86 137 3099 8269

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026