Forearm fracture postoperative pain, postoperative analgesia, chronic pain
Conditions
Interventions
Bupivacaine liposome group:Axillary nerve block with bupivacaine liposome 133 mg after operation
Ropivacaine group:Axillary nerve block with 0.25 % ropivacaine 10 ml at the end of operation.
Sponsors
Shaanxi 215 Hospital of nuclear industry
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.The age was 18-80 years old. 2.ASA grade I ~ III; 3.Cognitive function is normal, can cooperate with; 4.To be unilateral forearm fracture open reduction and internal fixation; 5.Agree to receive ultrasound-guided brachial plexus block anesthesia; 6.Voluntary participation and signing of informed consent.
Exclusion criteria
Exclusion criteria: 1.Allergic to local anesthetics or research drugs; 2.Puncture site infection; 3.Complicated with severe neurological diseases; 4.Severe liver and kidney dysfunction; 5.Coagulation disorders; 6.History of chronic pain or long-term use of opioids; 7.Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting state VAS score at 48 h; | — |
Secondary
| Measure | Time frame |
|---|---|
| The VAS scores at 24h, 48h and 72h after operation were recorded.;The pressing times of analgesia pump and the amount of sufentanil used within 24h, 48h and 72h.;Satisfaction of analgesic effect;The time of first remedial analgesia and the dose of remedial analgesics were recorded.;The degree and duration of motor block at 2 h, 6 h, 12 h, 24 h, 48 h and 72 h after operation were recorded.;Incidence of postoperative adverse reactions;length of hospital stay;The resting state VAS scores at 2 h, 6 h, 12 h, 24 h and 72 h after operation were recorded.;Gastrointestinal peristalsis recovery time; | — |
Countries
China
Contacts
Public ContactDu JianLong
Shaanxi 215 Hospital of Nuclear Industry
Outcome results
None listed