Infantile hypertrophic pyloric stenosis (infants undergoing open pyloromyotomy)
Conditions
Interventions
Normothermia:NA
Hypothermia:NA
Sponsors
Beijing Children's Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 0.3 Years
Inclusion criteria
Inclusion criteria: 1. The surgery was performed between January 2023 and August 2025; 2. Infants younger than 3 months old (i.e., corrected age at surgery not exceeding 3 months); 3. Diagnosed with hypertrophic pyloric stenosis and underwent pyloromyotomy (including open surgery or laparoscopic surgery); 4. Surgery was performed under general anesthesia with intubation, with continuous core temperature monitoring recorded during the procedure; 5. Complete perioperative data were obtained during surgery and anesthesia (including temperature, anesthesia records, awakening time, and extubation time, etc.).
Exclusion criteria
Exclusion criteria: 1. Abnormal body temperature before surgery: hypothermia (core temperature 38.0°C), which may affect intraoperative temperature assessment; 2. Children with congenital or acquired diseases that significantly affect temperature regulation (such as hypothyroidism/hyperthyroidism, metabolic syndrome, malignant hyperthermia susceptibility, etc.); 3. No monitoring of core temperature during surgery or missing temperature data; 4. Cases requiring postoperative transfer to the ICU with ongoing endotracheal intubation due to concurrent major surgery or critical conditions (unable to assess postoperative extubation time); 5. Preexisting severe respiratory diseases or neurological abnormalities (such as brain injury) that pose a high risk of delayed awakening, to avoid interfering with the evaluation of hypothermia effects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extubation time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Delayed extubation;PACU length of stay;PACU events; | — |
Countries
China
Contacts
Public ContactLi Gan
Beijing Children's Hospital Affiliated to Capital Medical University
Outcome results
None listed