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A Study on the Analgesic Effects of Different Volumes of Ropivacaine for Superficial Serratus Anterior Plane Block in Radical Mastectomy for Breast Cancer

A Study on the Analgesic Effects of Different Volumes of Ropivacaine for Superficial Serratus Anterior Plane Block in Radical Mastectomy for Breast Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117115
Enrollment
Unknown
Registered
2026-01-20
Start date
2026-01-31
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain

Interventions

R1:Serratus anterior block is performed with 10 ml of 0.5% ropivacaine
R2:Serratus anterior block is performed with 20 ml of 0.5% ropivacaine
R3:Serratus anterior block is performed with 30 ml of 0.5% ropivacaine

Sponsors

Yichang Central People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Female, aged 35 to 70 years old; (2) ASA grade I to III; (3) BMI 18 to 28 kg/m^2; (4) Patients with unilateral breast cancer scheduled for unilateral radical mastectomy.

Exclusion criteria

Exclusion criteria: (1) Patients allergic to ropivacaine and amide local anesthetics; (2) Patients with a history of alcohol or analgesic drug dependence; (3) Skin infection at the puncture site; (4) Coagulation disorders; (5) Severe systemic infection. (6) Nervous system disorders; (7) Patients with communication disorders who cannot cooperate; (8) Patients who are pregnant or plan to become pregnant within six months after surgery; (9) Other patients deemed unsuitable for this project by the researchers.

Design outcomes

Primary

MeasureTime frame
The VAS scores at rest and movement were evaluated at 2h, 6h, 12h, 24h, and 48h after surgery;Number of cases and times of rescue analgesia (single sufentanil 5ug);

Secondary

MeasureTime frame
Intraoperative sufentanil consumption;Intraoperative remifentanil consumption;Intraoperative propofol consumption;Block analgesia maintenance time ;Intraoperative vasoactive drug use;

Countries

China

Contacts

Public ContactMing Zhang

Yichang Central People's Hospital

281490716@qq.com+86 158 7253 9073

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026