Nonsuicide self injury
Conditions
Interventions
rTMS group:The stimulation protocol employed high-frequency (10 Hz) repetitive transcranial magnetic stimulation (rTMS). The stimulation sites targeted neural regions underlying both emotional regulat
Sham stimulation group:Sham Stimulation: The control condition will employ sham rTMS, delivered using a coil orientation or device setting that mimics auditory and tactile sensations of real stimulati
Healthy control group:NA
Sponsors
Shanghai Changzheng Hospital
Eligibility
Sex/Gender
All
Age
12 Years to 30 Years
Inclusion criteria
Inclusion criteria: Experimental and health controls: 1. Experimental group: (1) Adolescents and young adults aged 12–30 years (2) A history of recent self-injurious behavior, with at least one episode in the past month and a total of at least four episodes (3) Right-handed (4) No comorbid diagnosis of other severe mental illnesses (5) Able to cooperate with EEG and functional MRI scans, with no contraindications for MRI 2. Healthy control group: (1) Age-, gender-, and education level-matched to the NSSI group (2) No history of any mental disorders or self-injurious behavior
Exclusion criteria
Exclusion criteria: (1) Severe physical illnesses, psychotic disorders, perceptual disorders, substance dependence, or history of neurological diseases; (2) Metal implants in the head or history of cranial surgery; (3) Pregnancy or lactation; (4) Recent suicide attempts or severe suicidal tendencies.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Reward-punishment task accuracy;fMRI-EEG Related Changes; | — |
Primary
| Measure | Time frame |
|---|---|
| Self-injury; | — |
Countries
China
Contacts
Public ContactLiu Shiyuan
Shanghai Changzheng Hospital
Outcome results
None listed