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Effects of Intense Pulsed Light and Tea Tree Oil on Demodex-Related Meibomian Gland Dysfunction

Effects of Intense Pulsed Light and Tea Tree Oil on Demodex-Related Meibomian Gland Dysfunction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117086
Enrollment
Unknown
Registered
2026-01-20
Start date
2026-01-31
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Demodex-Related Meibomian Gland Dysfunction

Interventions

TTO Group:Tea tree oil wiper

Sponsors

Tianjin Medical University Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years old; 2.Meets the diagnostic criteria for MGD-related dry eye syndrome as specified in the Chinese Consensus on Dry Eye Syndrome: Examination and Diagnosis (2020). 3.Demodex mites on eyelashes;

Exclusion criteria

Exclusion criteria: 1.Age > 75 years old; 2.Tear gland disorders, active inflammation, entropion or ectropion of the eyelid, uveitis, and other eye diseases; 3.Eye trauma, chemical burns, history of eye surgery, use of corneal contact lenses, systemic rheumatic or immune diseases, dry syndrome, pregnancy or lactation; 4.History of eye medication use within one week prior to the study;

Design outcomes

Primary

MeasureTime frame
OSDI score;

Secondary

MeasureTime frame
Corneal staining score;Manifest refraction;Meibomian gland score;Lipid layer thickness;Non-invasive tear film break-up time, NIKBUT;Demodex count;

Countries

China

Contacts

Public ContactHuang Yue

Tianjin Medical University Eye Hospital

1097813271@qq.com+86 15620662542

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026