Demodex-Related Meibomian Gland Dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years old; 2.Meets the diagnostic criteria for MGD-related dry eye syndrome as specified in the Chinese Consensus on Dry Eye Syndrome: Examination and Diagnosis (2020). 3.Demodex mites on eyelashes;
Exclusion criteria
Exclusion criteria: 1.Age > 75 years old; 2.Tear gland disorders, active inflammation, entropion or ectropion of the eyelid, uveitis, and other eye diseases; 3.Eye trauma, chemical burns, history of eye surgery, use of corneal contact lenses, systemic rheumatic or immune diseases, dry syndrome, pregnancy or lactation; 4.History of eye medication use within one week prior to the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OSDI score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Corneal staining score;Manifest refraction;Meibomian gland score;Lipid layer thickness;Non-invasive tear film break-up time, NIKBUT;Demodex count; | — |
Countries
China
Contacts
Tianjin Medical University Eye Hospital