Cesarean Scar Defect
Conditions
Interventions
Experimental group:Use porcine fibrin sealant and perform double-layer suturing
Control group:Standard double-layer suturing
Sponsors
Shulan (Hangzhou) Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.Age 18–40 years, gestational age >= 38 weeks; 2.Pregnant women with singleton pregnancies undergoing elective primary cesarean sections; 3.Sign the informed consent form, committing to complete at least 6 months of postoperative follow-up.
Exclusion criteria
Exclusion criteria: 1.Multiple pregnancies, placenta previa, placenta accreta; 2.History of uterine surgery (e.g., myomectomy) or uterine malformations; 3.Premature rupture of membranes or genital tract infections (including vaginitis, cervicitis, chorioamnionitis); 4.Emergency cesarean section or severe intraoperative complications (e.g., complex suturing of uterine incision tears, massive hemorrhage requiring blood transfusion); 5.Allergy to porcine fibrin sealant components or a history of severe allergic diseases; 6.Prolonged preoperative use of anticoagulants, glucocorticoids, or immunosuppressants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Residual myometrial thickness, RMT; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of Uterine Scar Diverticulum Formation;Diverticulum length (mm), Diverticulum depth (mm);Blood loss during cesarean section (ml);Incidence of Abnormal Vaginal Bleeding;Incidence of adverse reactions;Incidence of postpartum hemorrhage;Average operating time (min);Incidence of severe scar defects; | — |
Countries
China
Contacts
Public ContactGAN KWANG HANN
Shulan (Hangzhou) Hospital
Outcome results
None listed