Hepatocellular carcinoma
Conditions
Interventions
FOLFOX-HAIC group (Hepatic Artery Infusion Chemotherapy):NA
RALOX-HAIC group (Hepatic Artery Infusion Chemotherapy):NA
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years old; 2. Subjects who were diagnosed with HCC by histopathology or clinically diagnosed with HCC according to the "Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2024 Edition)"; 3. CNLC staging: IIIa or IIIb (BCLC-C stage); 4. Child-Pugh liver function rating: Grade A or Grade B; 5. ECOG PS score: 0~2 points; 6. There is at least one measurable lesion (according to RECIST v1.1); 7. Has not received other anti-tumor treatments before.
Exclusion criteria
Exclusion criteria: 1. Patients with autoimmune diseases; 2. Patients with a history of esophageal or gastric variceal bleeding; 3. Patients who are pregnant or breastfeeding; 4. Patients with other malignant tumors besides HCC.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-free survival;objective response rate;disease control rate; | — |
Countries
China
Contacts
Public ContactXuefeng Kan
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed