Painless colonoscopy
Conditions
Interventions
Non-sulfate magnesium group (Group C):Ten minutes before anesthesia induction, an equal volume of saline (placebo) was administered intravenously.
Magnesium sulfate group (Group E):Ten minutes before anesthesia induction, administer magnesium sulfate 20 mg/kg intravenously (diluted to 100 ml with saline).
Sponsors
Lu'an City Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Sign the informed consent form; (2) Patients undergoing painless colonoscopy at this hospital; (3) Age 18-65 years; (4) ASA classification (American Society of Anesthesiologists Physical Status) I or II
Exclusion criteria
Exclusion criteria: (1) Individuals allergic to alfentanil, propofol, magnesium sulfate, or soy and eggs; (2) Severe cardiac, pulmonary, hepatic, or renal dysfunction (ASA class III or above); (3) Renal failure (affecting magnesium ion excretion); (4) History of long-term use of opioids or sedatives; (5) BMI > 35 kg/m² or at risk for difficult airway; (6) Currently participating in another clinical trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative body movement; | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug dosage: total dose of propofol (mg/kg), total dose of alfentanil (µg/kg);;Awakening time (the time from stopping the medication to reaching a Steward score =6);Using the Visual Analog Scale (VAS, 0-10 points) to assess the patient's pain.;Incidence of postoperative nausea and vomiting (PONV);Patient baseline, before anesthesia induction, 5 minutes after the start of the examination, and after full recovery vital signs; | — |
Countries
China
Contacts
Public ContactChen Jianxiang
Lu'an City Traditional Chinese Medicine Hospital
Outcome results
None listed