Cerebral haemodynamic changes throughout the anaesthetic emergence to recovery process
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged >= 40 years and <= 60 years; 2. Having undergone gynecological laparoscopic surgery under general anesthesia; 3. American Society of Anesthesiologists (ASA) physical status classification of Grade I-III; 4. Willing to participate in this study and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1. Severe anemia (hemoglobin [Hb] 4 hours; 3. Severe visual, auditory, or speech dysfunction; 4. Severe abnormal functions of the heart, liver, kidney, or lung; 5. Confirmed or suspected abuse of or long-term use of narcotic sedative analgesics; 6. A history of allergy to conventional anesthetics or contraindications to them;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative mean and change in cerebral hemoglobin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anesthesia-related indicators (including ASA classification, history of prior anesthesia; anesthetic method, duration of anesthesia, time to loss/recovery of consciousness, duration of mechanical ventilation, duration of special positions [head-up tilt, head-down tilt], surgical procedure, surgical duration, doses of anesthetic agents, doses of adjuvant drugs, volumes of fluids and blood products administered, intraoperative blood gases, perioperative vital signs [blood pressure, heart rate, res; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Army Medical University, PLA