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Impact of Propofol versus Sevoflurane on Prefrontal Cerebral Functional Networks in Patients Undergoing Gynecological Laparoscopic Surgery Based on Near-Infrared Spectroscopy: A Single-Center, Retrospective Cohort Study

Impact of Propofol versus Sevoflurane on Prefrontal Cerebral Functional Networks in Patients Undergoing Gynecological Laparoscopic Surgery Based on Near-Infrared Spectroscopy: A Single-Center, Retrospective Cohort Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117043
Enrollment
Unknown
Registered
2026-01-19
Start date
2025-11-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral haemodynamic changes throughout the anaesthetic emergence to recovery process

Interventions

Propofol groups:None
Sevoflurane groups:None

Sponsors

The Second Affiliated Hospital of Army Medical University, PLA
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged >= 40 years and <= 60 years; 2. Having undergone gynecological laparoscopic surgery under general anesthesia; 3. American Society of Anesthesiologists (ASA) physical status classification of Grade I-III; 4. Willing to participate in this study and sign the informed consent form;

Exclusion criteria

Exclusion criteria: 1. Severe anemia (hemoglobin [Hb] 4 hours; 3. Severe visual, auditory, or speech dysfunction; 4. Severe abnormal functions of the heart, liver, kidney, or lung; 5. Confirmed or suspected abuse of or long-term use of narcotic sedative analgesics; 6. A history of allergy to conventional anesthetics or contraindications to them;

Design outcomes

Primary

MeasureTime frame
Perioperative mean and change in cerebral hemoglobin;

Secondary

MeasureTime frame
Anesthesia-related indicators (including ASA classification, history of prior anesthesia; anesthetic method, duration of anesthesia, time to loss/recovery of consciousness, duration of mechanical ventilation, duration of special positions [head-up tilt, head-down tilt], surgical procedure, surgical duration, doses of anesthetic agents, doses of adjuvant drugs, volumes of fluids and blood products administered, intraoperative blood gases, perioperative vital signs [blood pressure, heart rate, res;

Countries

China

Contacts

Public ContactLi Hong

The Second Affiliated Hospital of Army Medical University, PLA

lh78553@tmmu.edu.cn+86 136 0838 0123

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026