Transfusion-Dependent Thalassemia (TDT)
Conditions
Interventions
Control group:None
Observation group:None
Sponsors
Liuzhou Worker's Hospital
Eligibility
Sex/Gender
All
Age
6 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with Transfusion-Dependent Thalassemia (TDT); 2.Aged 6 years or older, with no gender restrictions; 3.Receiving regular transfusion therapy in Liuzhou City, with a transfusion frequency of at least once every 4 weeks; 4.Patients or their guardians must sign an informed consent form agreeing to participate in this study.
Exclusion criteria
Exclusion criteria: 1.Patients with Non-Transfusion-Dependent Thalassemia (NTDT); 2.Patients with other severe comorbidities (e.g., malignancies, severe infections, etc.); 3.Patients who have undergone hematopoietic stem cell transplantation within the recent period (within the past 6 months); 4.Patients who are unable to comply with the research follow-up requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood matching duration;Number of blood transfusions, volume of blood transfused;Interval between blood transfusions;Incidence of adverse reactions to blood transfusion;Irregular antibody production rate;Positive rate of the direct antiglobulin test;Incidence of difficulty in matching blood;Hemoglobin increase status;Blood transfusion medical expenses; | — |
Countries
China
Contacts
Public ContactTang Si
Liuzhou Worker's Hospital
Outcome results
None listed