Benign or low-grade malignant mandibular tumors
Conditions
Interventions
Control group:Mirror imaging of the contralateral healthy mandible was used to reconstruct the mandibular model, facilitating single-layer MMF grafting with simultaneous implant placement. The process
obtaining intraoral and occlusal scan data using an intraoral digital scanner
simulating mandibular resection, fibula flap shaping and positioning, implant placement, and prosthetic restoration
mirror copying and fitting adjustment of the morphology and position of the contralateral normal mandible
3D printing a resin model and pre-bending titanium plates
designing and printing mandibular osteotomy guides, fibula osteotomy and shaping guides (including implant sleeves).
Trial group:Virtual reconstruction based on 3D mandibular measurements for assisted folded fibular graft transplantation with simultaneous implant placement. Specifically: acquire CBCT and CTA data, i
obtain intraoral and occlusal scans using an intraoral digital impression scanner
simulate mandibular resection, folding and shaping of the fibular flap, implant placement, and prosthodontic rehabilitation
measure precise parameters including FH-MP, Co-Go, Go-Me, GoR-GoL, and GoR-Me-GoL and integrate them into the model
determine folding method (double-layer or one-and-a-half layer) based on mandibular height, occlusal space, and fibular height
update the model and align it with the precision model
3D print resin models and pre-bend titanium plates
design and print mandibular osteotomy guides, fibular osteotomy and shaping guides (with implant sleeves).
Sponsors
Beijing Stomatological Hospital , Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-60 years, regardless of gender; 2. Preoperative pathological diagnosis confirmed benign or low-grade malignant mandibular tumors; 3. Anticipated mandibular defect following tumor resection requiring free fibula flap transplantation for reconstruction; 4. Patients with functional rehabilitation and reconstruction needs.
Exclusion criteria
Exclusion criteria: 1. Patients with poor systemic conditions who cannot tolerate general anesthesia and surgery; 2. Patients with poor local vascular conditions or anatomical variations in the peroneal artery and vein system; 3. Diabetic patients with uncontrolled conditions (2-hour postprandial blood glucose >11.1 mmol/L); 4. Pregnant or lactating women; 5. Individuals with mental or intellectual disabilities; 6. Patients unable to undergo intraoral digital scanning, such as those with oral mucosal diseases, severe respiratory disorders, asthma, Parkinson’s disease, hyperactivity disorders, or moderate-to-severe limited mouth opening.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Facial contour restoration status; | — |
Secondary
| Measure | Time frame |
|---|---|
| The fusion condition of the fibula with the mandible; | — |
Countries
China
Contacts
Public ContactYi Qu
Beijing Stomatological Hospital , Capital Medical University
Outcome results
None listed