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Non-inferiority of Adaptive Minute Ventilation Compared with Adaptive Support Ventilation in Transport Ventilators: A Prospective Randomized Controlled Trial

Non-inferiority of Adaptive Minute Ventilation Compared with Adaptive Support Ventilation in Transport Ventilators: A Prospective Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117001
Enrollment
Unknown
Registered
2026-01-19
Start date
2026-02-14
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory failure, heart failure, etc.

Interventions

Trial group:Use AMV mode during transport
Control group:Use ASV mode during transport

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age >=18 years old and =1 hour of mechanical ventilation prior to transport; 3. Patients requiring transport; 4. The patient (or their legal representative or guardian) agrees to participate in this trial and understands and signs the "Subject Informed Consent Form".

Exclusion criteria

Exclusion criteria: 1. Patients who have used or are currently using AMV or ASV modes; 2. Sepsis patients with SOFA score >15; 3. Patients with APACHE II score >30; 4. Patients using ECMO (extracorporeal membrane oxygenation); 5. Patients who have suffered cardiac arrest and whose resuscitation has not been completed; 6. Patients in shock or with hemodynamic instability whose treatment is incomplete; 7. Pulmonary bullae, pneumothorax without closed chest drainage, especially tension pneumothorax; 8. Massive hemoptysis, and patients with respiratory failure caused by massive hemoptysis or severe aspiration; 9. Hypercapnia-related respiratory failure; 10. Patients with severe mental disorders; 11. Pregnant women; 12. Patients deemed unsuitable for participation in the trial by clinicians.

Design outcomes

Primary

MeasureTime frame
Change in carbon dioxide partial pressure;

Secondary

MeasureTime frame
Oxygenation index change value;Airway peak pressure;Dynamic compliance;Rapid shallow breathing index;Healthcare worker satisfaction rating;Number of ventilator alarms and manual interventions during transport;

Countries

China

Contacts

Public ContactLiu Jihai

Peking Union Medical College Hospital

liujihai1977@aliyun.com+86 10 6915 9100

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026