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Development and Validation of a Multimodal Feature-Based Prediction Model for Post-Dissection Distal Aortic Remodeling Adverse Risk

Development and Validation of a Multimodal Feature-Based Prediction Model for Post-Dissection Distal Aortic Remodeling Adverse Risk

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600116988
Enrollment
Unknown
Registered
2026-01-18
Start date
2025-01-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic dissection

Interventions

Observation group:None

Sponsors

Beijing Anzhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: a. Aged >= 18 years b. Underwent aortic computed tomography angiography (CTA) within 3 months preoperatively c. Underwent a follow-up aortic computed tomography angiography (CTA) within 1 year after surgery d. Presence of distal residual dissection after surger

Exclusion criteria

Exclusion criteria: a. Perioperative mortality b. Developed Type I endoleak postoperatively c. Stent-induced new entry tears at the proximal and distal ends of the stent-graft d. Developed retrograde dissection or underwent reoperation on the aorta for other reasons postoperatively e. Aortic penetrating ulcer (APU) f. Traumatic aortic dissection g. Aortic dissection secondary to hereditary connective tissue disorders such as Marfan syndrome h. Aortic inflammatory diseases i. Poor image quality of aortic CTA, making it unavailable for analysis

Design outcomes

Primary

MeasureTime frame
High Relative Particle Residence Time Fraction;Total Aortic Diameter;False Lumen Diameter;True Lumen Diameter;Poor distal aortic remodeling occurring within 1 year postoperatively.;

Secondary

MeasureTime frame
Diameter of the ascending aorta;Diameter of the aortic sinus;Pericardial effusion;Length of Stay in the Intensive Care Unit;Postoperative recovery time;Postoperative Cerebral hemorrhage;Postoperative Cerebral infarction;Postoperative Dialysis;Postoperative Myocardial Infarction;Postoperative Atrial fibrillation;Cardiac tamponade;Postoperative Lung infection;Pleural effusion;Respiratory failure;Postoperative hemorrhage;In-hospital Death;Postoperative renal function impairment;limb paralysis;limb ischemia;paraplegia;secondary surgery;B-type natriuretic peptide;Cardiac Troponin I;Neutrophil Percentage;Lymphocyte Percentage;Red Blood Cell;Venous Hemoglobin;Venous Platelet Count;Glycated Hemoglobin;Triiodothyronine;Thyroxine;Thyroid-Stimulating Hormone;Prothrombin Time;Activated Partial Thromboplastin Time;Plasma D-dimer;Alanine Aminotransferase;Aspartate Aminotransferase;Uric Acid;Creatinine;Glomerular Filtration Rate;High-Density Lipoprotein Cholesterol;Low-Density Lipoprotein Cholesterol;High-Sensitivity C-Reactive Protein;Wall Shear Stress;Inter-chamber Pressure Difference;First Equilibrium Point of Pressure Difference;Pressure Equilibrium Point;Energy Loss;Time-Averaged Wall Shear Stress;Oscillatory Shear Index;Relative Particle Residence Time;Aortic Volume;True Lumen Volume;False Lumen Volume;Intramural Stress;Time-Averaged Intramural Stress;

Countries

China

Contacts

Public ContactYuan Xue

Beijing Anzhen Hospital

xueyuan@mail.ccmu.edu.cn+86 188 1152 3278

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026