Dental Cares
Conditions
Interventions
Severe tooth caries:None
Slight tooth caries:None
Control:None
Collection of dental pulp fibroblasts:None
Sponsors
Shanghai tenth People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Voluntarily participate in this experiment; 2.Able to participate in the test on time and complete the entire test step; 3.Patients requiring extraction of deep caries caries; 4.Patients who need to have their healthy premolars extracted due to orthodontics; 5.Signed informed consent;
Exclusion criteria
Exclusion criteria: 1.Suffering from serious physical diseases (as judged by clinical examiners), including but not limited to irregular heart rate, uncontrolled hypertension, diabetes, hepatitis caused by various causes, renal failure, etc. 2.Any mental illness or other illness that could lead to a legally recognized limitation of capacity; 3.Incapacity for civil conduct or refusal to participate in the trial; 4.After tooth extraction, there are hidden diseases that have not been found in previous examinations, such as enamel hypoplasia, early caries demineralization, tooth discoloration, and irremovable calculus on the tooth surface; 5.The crown is damaged during extraction for various reasons; 6.Those who are judged by a physician to be unable to be enrolled;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolomics;Metagenomics;Transcriptomics; | — |
Countries
China
Contacts
Public ContactHang Yuan
Shanghai tenth People's Hospital
Outcome results
None listed