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Research on the effects and brain mechanisms of transcranial magnetic stimulation combined with exercise intervention on ADHD patients of different age groups

Research on the effects and brain mechanisms of transcranial magnetic stimulation combined with exercise intervention on ADHD patients of different age groups

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600116963
Enrollment
Unknown
Registered
2026-01-17
Start date
2026-02-15
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention deficit hyperactivity disorder

Interventions

Transcranial magnetic stimulation group:Non-invasive transcranial magnetic stimulation administered in person by trained professionals
20–30 minutes per session, 3 times per week, for 12 weeks (total of 36 sessions).
Exercise group:Exercise training supervised by trained professionals
45 minutes per session, 3 times per week, for 12 weeks (total of 36 sessions).
Transcranial magnetic stimulation combined exercise group:Transcranial magnetic stimulation combined exercise intervention
Wait-list group:No intervention, waiting-list
Healthy group:None

Sponsors

School of Sports Medicine and Rehabilitation, Beijing Sport University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for ADHD in children and adults as defined by the Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) published by the American Psychiatric Association or the 11th Edition of the International Classification of Diseases (ICD-11), specifically: (1) Attention deficit: Difficulty sustaining attention in tasks lacking high-level stimulation or frequent rewards; easily distracted; poor organization and orderliness in task performance; (2) Hyperactivity/impulsivity: Excessive motor activity (hyperactivity); difficulty remaining still; particularly evident in structured situations requiring self-control; tendency to respond immediately to stimuli (impulsivity) without considering risks or consequences; (3) The severity of attention deficit and/or hyperactivity/impulsivity exceeds the normal range for age and intelligence, significantly impairing academic, occupational, and social functioning; (4) Symptoms typically emerge during the developmental period, manifesting as a persistent pattern of attention deficit and/or hyperactivity-impulsivity (lasting at least 6 months) and must be observable in multiple settings; clinically, patients are diagnosed as: ADHD, predominantly inattentive presentation; ADHD, predominantly hyperactive/impulsive presentation; ADHD, combined presentation; 2. Wechsler Intelligence Scale IQ score >= 80; 3. Age 5–30 years, either sex. Healthy control group: None

Exclusion criteria

Exclusion criteria: Excluding mental disorders other than ADHD, such as mental retardation, pervasive developmental disorders, and emotional disorders, etc. Contraindications for rTMS (such as intracranial metal implantation, implantable electronic devices, etc.) and sports contraindications.

Design outcomes

Primary

MeasureTime frame
Motor ability;Executive function;

Secondary

MeasureTime frame
Writing ability;Sleep quality;Neural activity of the brain;EMG, EEG, eye tracking;

Countries

China

Contacts

Public ContactZhu Feilong

School of Sports Medicine and Rehabilitation, Beijing Sport University

zhufeilong1559@163.com+86 150 8047 1559

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026