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Development and Validation of a Prognostic Model for Neurological Deterioration in Acute Posterior Circulation Cerebral Infarction

Development and Validation of a Prognostic Model for Neurological Deterioration in Acute Posterior Circulation Cerebral Infarction

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600116946
Enrollment
Unknown
Registered
2026-01-16
Start date
2026-01-16
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute posterior circulation cerebral infarction

Interventions

Gold Standard:Clinical manifestations and brain MRI report.

Sponsors

Peking University Shenzhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients with acute posterior circulation cerebral infarction who were treated at the Department of Neurology, Peking University Shenzhen Hospital, Shenzhen, from January 1, 2019, to April 1, 2025; 2.Meeting the diagnostic criteria for acute cerebral infarction as outlined in the "Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke (2023 edition)" and the infarction occurs in the posterior circulation area. 3.All patients were admitted within 24 hours of onset and received standard antiplatelet and statin therapy. 4.Age >=18 years. 5.No gender-based restriction.

Exclusion criteria

Exclusion criteria: 1.Cannot make a judgment due to incomplete clinical data; 2.Patients who have undergone intravenous thrombolysis or endovascular treatment; 3.Anterior circulation infarction, hemorrhagic stroke, or transient ischemic attack (TIA); 4.Inability and refusal to assess neurological deficits within 7 days of admission; 5.Concomitant severe infections, malignancies, severe cardiopulmonary diseases, hepatic or renal failure, or hematologic disorders. 6.MRI/DWI confirmed a non-posterior circulation lesion; 7.Key outcome indicators (such as NIHSS scores) are missing; 8.Refused follow-up.

Design outcomes

Primary

MeasureTime frame
Neurological Deterioration;Sensitivity;Specificity;

Countries

China

Contacts

Public ContactYi Li

Peking University Shenzhen Hospital

yilitj@hotmail.com+86 7558392333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026